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Virtsarakon ekstrofia on synnynnäinen epämuodostuma, sikiöaikana tapahtunut virtsarakon ja -putken sulkeutumatta jääminen. Jo raskauden ensimmäisinä viikkoina tapahtuva häiriö on aiheuttajaltaan tuntematon. Useimmat tapaukset ovat satunnaisia. Epämuodostumasta kärsivien rakko on kokonaan avoin, alavatsan ihossa kiinni oleva epiteelipintainen levy. Epämuodostumaan liittyy useita muita poikkeavuuksia, joista jopa kaikki voivat esiintyä yhdessä…

Introduction. Bladder exstrophy, one of the most serious congenital ekstrofiamalformations, is characterized by a spectrum of anomalies involving the。

Bladder exstrophy is a congenital anomaly that exists along the spectrum of the exstrophy-epispadias complex, and most notably involves protrusion of the urinary bladder through a defect in the abdominal wall. Its presentation is variable, often including abnormalities of the bony pelvis, pelvic floor, and genitalia. The underlying embryologic mechanism leading to bladder exstrophy is unknown, though it is thought to be in part due to failed reinforcement of the cloacal membrane b…

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